The incidence, mortality, and medical costs of clostridium difficile infection (CDI) are at their highest levels in history, according to a report by the Centers for Disease Control and Prevention.
For the report, researchers looked at data from the Emerging Infections Program, NHSN, and c diff prevention programs in Illinois, Massachusetts, and New York.
Key findings include:
- 94% of all CDIs were related to various precedent and concurrent health-care exposures
- Of these patients, 75% had CDI onset outside of a hospital.
- Some cases occurred in patients who were exposed to multiple settings including nursing homes and hospitals.
- Mortality from CDI increased from 3,000 deaths per year during 1999–2000 to 14,000 during 2006–2007; over 90% of these cases were in patients aged 65 or older.
- Hospital-onset CDI are estimated to cost $5,042–$7,179 per case.
- Much of the recent increase in the incidence and mortality of CDIs is attributed to the emergence and spread of a hypervirulent, resistant strain of C. difficile.